Feasibility of Brain Lesion Characterization at 1 . 5 T – Whole-Brain Susceptibility Mapping Using A Homogeneous Lesion Constraint


Journal article


F. Schweser, A. Deistung, B. W. Lehr, J. Reichenbach
2009

Semantic Scholar
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Cite

APA
Schweser, F., Deistung, A., Lehr, B. W., & Reichenbach, J. (2009). Feasibility of Brain Lesion Characterization at 1 . 5 T – Whole-Brain Susceptibility Mapping Using A Homogeneous Lesion Constraint.

Chicago/Turabian
Schweser, F., A. Deistung, B. W. Lehr, and J. Reichenbach. “Feasibility of Brain Lesion Characterization at 1 . 5 T – Whole-Brain Susceptibility Mapping Using A Homogeneous Lesion Constraint” (2009).

MLA
Schweser, F., et al. Feasibility of Brain Lesion Characterization at 1 . 5 T – Whole-Brain Susceptibility Mapping Using A Homogeneous Lesion Constraint. 2009.


Abstract

INTRODUCTION – Susceptibility weighted MR phase data provide anatomical contrast complementary to magnitude data [1-3] by directly reflecting local magnetic field changes. Recently, ambitious approaches were presented for the challenging problem of inverting the magnetic field to magnetic susceptibility [4-6]. However, most of the presented studies demonstrated fairly poor fidelity, were ex vivo studies, required excessive data acquisition, and/or data were acquired at ultra-high field strength. In this contribution, we present an improved method for high-quality whole-brain susceptibility mapping based on a single standard clinical low-field SWIdataset. Feasibility of in vivo lesion characterization is demonstrated for clinical patient data (n=10). Furthermore, it was shown by numerical simulation that only minimal susceptibility differences with respect to the surrounding tissue may be obtained for cavernous lesions.